Just picked up my daughter from her freshman year at MIZZOU and thought I'd share our favorites from the year:

#1 for Breakfast:
ERNIE'S
Art Deco-design old diner-style joint. Line out the door but it moves quickly! A COMO classic - most go for breakfast. Sit at counter, or community table -- can't go wrong here for greasy but great breakfast food.

Lunch/Dinner: Other than our tailgate at the MIZZOU game...where we serve killer shish kebobs--

FLAT BRANCH
Micro-brewery near campus. Saw a man in a kilt there last month. Great crowd around the bar and in restaurant. Twisted Pretzel = their specialty appetizer. YUM. Good all-around food and drink. Awesome salmon! Fun crowd. Outdoor seating.
http://www.flatbranch.com/home.asp

44 STONE
Car Required - Cannot walk from campus. Excellent "British Pub" in a strip mall South of campus. Great ambiance, food, beer. Recommend for lunch or dinner. Great find! Outdoor seating.
http://44stonepub.com/

ROME:
Just your basic Italian place -- pizza, pasta, salads -- but reliable stuff. Not fancy -- but you don't always need fancy!
http://www.dinerome.com/

ADDISON'S:
Great for after the game.
http://addisonssophias.com/addisons/

Drinks:

QUINTON'S:
Venue is great -- series of tiered, glass-enclosed balconies with an awesome sunset view of COMO with church bell towers adding to the interest... A touch of South Beach in MO.
http://www.quintonsandtonic.com/quintons-patio.php

Numerous other bars -- but those are easy to spot and undergrads will always know the way...no need to single them out here!