Expect sudden changes in street-address numbering as streets pass through neighborhoods, then incorporated cities, then back into neighborhoods. This can be most bewildering on Robertson Boulevard, an otherwise useful north-south artery that, by crossing through L.A., West Hollywood, and Beverly Hills, dips in and out of several such numbering shifts in a matter of miles.
In Santa Monica, odd numbers switch over from the north and west sides of streets to the south and east sides.
There are plenty of identical or extremely similar street names in L.A., so be as specific as you can when getting or checking directions.