Car Travel

Interstate 77 leads into Columbia from the north, Interstate 26 runs through north-south, and Interstate 20 east-west. Interstate 85 provides access to Greenville, Spartanburg, Pendleton, and Anderson. Interstate 26 runs from Charleston through Columbia to the Upstate, connecting with Interstate 385 into Greenville. Car rental by all the national chains is available at the airports in Columbia and Greenville.