401 Richmond
Packed with galleries, interesting shops, and two cafés, this beautifully refurbished industrial building is an essential component of Toronto's contemporary art scene. Check out YYZ Artists' Outlet, which holds consistently engaging shows, or Gallery 44 for contemporary photography. There's also the respected artist collective Red Head Gallery. Don't miss well-stocked Swipe for books on all things design and Spacing for stylish Toronto-themed T-shirts, prints, and knickknacks.